Product Datasheet  
ZBED3 Antibody  
Catalog Number: 24869  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q96IU2
    Gene ID:84327
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 15 amino acid peptide from near the carboxy terminus of human ZBED3.
  • reactivity：  
  • Hu
  • appl_detail：  
  • other_names：  
  • Zinc finger BED-type domain containing 3
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2.
  • Applications：  
  • ELISA WB ICC
  • Background：  
  • Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression.



 
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