Product Datasheet
MettL7B Antibody
Catalog Number: 24791
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q6UX53
Gene ID:196410
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a 13 amino acid peptide near the amino terminus of human MettL7B.
- other_names:
- Methyltransferase-like protein 7B
- Purification:
- Affinity chromatography purified via peptide column
- Specificity:
- This MettL7B antibody is predicted to not cross-react with MettL7A.
- Applications:
- ELISA WB IHC
- Background:
- MettL7B belongs to the methyltransferase superfamily. It is a probable methyltransferase. Methyltransferase is a type of transferase enzyme which transfers a methyl group from a donor to an acceptor. Often methylation occurs on nucleic bases in DNA or amino acids in protein structures. DNA methylation is often utilized to silence and regulate genes without changing the original DNA sequence. DNA methylation may be necessary for normal growth from embryonic stages in mammals. When mutant embryonic stem cells lacking the murine DNA methyltransferase gene were introduced to a germline of mice they caused a recessive lethal phenotype. Methylation may also be linked to cancer development as methylation of tumor suppressor genes promotes tumorgenesis and metastasis.
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