Product Datasheet  
IL-17 Antibody  
Catalog Number: 24789  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q16552
    Gene ID:3605
  • Form of Antibody:  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage:  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen:  
  • Raised against a 19 amino acid peptide from near the center of human IL-17A.
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • other_names:  
  • Interleukin-17, IL-17A, CTLA8
  • Purification:  
  • Affinity chromatography purified via peptide column
  • Specificity:  
  • Applications:  
  • ELISA WB
  • Background:  
  • Interleukin 17 (IL-17) is a family of pro-inflammatory cytokines produced by activated T cells and is thought to have a major role in the initiation and perpetuation of rheumatoid arthritis. IL-17 regulates the activities of NF-κB and mitogen-activated protein kinases such as ERK and JNK. In addition, IL-17 stimulates the expression of IL-6 and cyclooxygenase-2 and enhances the production of nitric oxide. IL-17-producing T helper cells (TH-17 cells) have been the subject of much attention due to the importance of IL-17 in the pathogenesis of autoimmune inflammation. Because of its role in autoimmune diseases, it is thought that targeting the production and action of IL-17 would be beneficial therapeutically in these diseases.



 
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