Product Datasheet
RASSF6 Antibody
Catalog Number: 25373
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot:Q6ZTQ3
Gene ID:166824
- Form of Antibody:
- Supplied in PBS containing 0.02% sodium azide.
- Storage:
- Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
- Immunogen:
- Raised against a 14 amino acid peptide near the center of human RASSF6.
- other_names:
- Ras association, RalGDS, AF-6, domain family 6
- Purification:
- Affinity chromatography purified via peptide column
- Specificity:
- At least four isoforms of RASSF6 are known to exist. RASSF6 antibody is predicted to not cross-react with other RASSF family members.
- Background:
- RASSF family proteins are tumor suppressors that are frequently downregulated during the development of human cancer. RASSF6 (Ras association (RalGDS/AF-6) domain family member 6), a member of RASSF family, acts as a Ras effector protein / tumor suppressor. RASSF6 contains one Ras-associating domain and one SARAH domain. It is involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. Defects in RASSF6 may facilitate viral NFκ-B pathway and may play a vital role in infection.
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