Product Datasheet  
RASSF6 Antibody  
Catalog Number: 25373  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q6ZTQ3
    Gene ID:166824
  • Form of Antibody:  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage:  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen:  
  • Raised against a 14 amino acid peptide near the center of human RASSF6.
  • reactivity:  
  • Hu
  • appl_detail:  
  • other_names:  
  • Ras association, RalGDS, AF-6, domain family 6
  • Purification:  
  • Affinity chromatography purified via peptide column
  • Specificity:  
  • At least four isoforms of RASSF6 are known to exist. RASSF6 antibody is predicted to not cross-react with other RASSF family members.
  • Applications:  
  • ELISA WB
  • Background:  
  • RASSF family proteins are tumor suppressors that are frequently downregulated during the development of human cancer. RASSF6 (Ras association (RalGDS/AF-6) domain family member 6), a member of RASSF family, acts as a Ras effector protein / tumor suppressor. RASSF6 contains one Ras-associating domain and one SARAH domain. It is involved in the induction of apoptosis, through both caspase-dependent and caspase-independent pathways. Defects in RASSF6 may facilitate viral NFκ-B pathway and may play a vital role in infection.



 
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