Product Datasheet  
AP3S1 Antibody  
Catalog Number: 25323  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q92572
    Gene ID:1176
  • Form of Antibody:  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage:  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen:  
  • Raised against a 19 amino acid peptide near the center of human AP3S1.
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • other_names:  
  • CLAPS3, Clathrin-associated, assembly, adapter protein, adaptor-related protein complex 3, Sigma-3A-adaptin, AP-3 complex subunit sigma-3A
  • Purification:  
  • Affinity chromatography purified via peptide column
  • Specificity:  
  • At least three isoforms of AP3S1 are known to exist; this antibody will detect the two larger isoforms. AP3S1 antibody is predicted to not cross-react with other AP3 protein family members.
  • Applications:  
  • ELISA WB
  • Background:  
  • AP3S1 belongs to the adaptor complexes 3 (AP3) small subunit family which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3 is an heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). AP3S1 Interacts with AGAP1 and may play an important role in carcinoma.



 
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