Product Datasheet  
Rim3 Antibody  
Catalog Number: 24633  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q9UJD0
    Gene ID:9783
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 17 amino acid peptide from near the amino terminus of human Rim3.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • other_names：  
  • Rab3-interacting molecule 3, regulating synaptic membrane exocytosis 3, RIM3 gamma, RIMS3, NIM3
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • This antibody is predicted to have no cross-reactivity to other Rim proteins.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity.



 
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