Product Datasheet  
Slitrk3 Antibody  
Catalog Number: 24632  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • O94933
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 14 amino acid peptide from near the carboxy terminus of human Slitrk3.
  • reactivity：  
  • Hu Ms
  • appl_detail：  
  • other_names：  
  • SLIT and NTRK-like family 3
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • This antibody is predicted to have no cross-reactivity to other Slitrk proteins.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • SLIT and NTRK-like family 3 (Slitrk3) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the protein family. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk3 inhibited neurite outgrowth in cultured neurons, suggesting that these proteins are involved in the control of neurite outgrowth.



 
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