Product Datasheet  
TEM2 Antibody  
Catalog Number: 24591  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Q96D21
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 15 amino acid peptide near the carboxy terminus of the human TEM2.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • other_names：  
  • Tumor endothelial marker 2, Ras homolog enriched in striatum, Rhes, RASD2
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.



 
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