Product Datasheet  
STEAP3 Antibody  
Catalog Number: 24568  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q658P3
    Gene ID:55240
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 15 amino acid peptide from near the amino terminus of human STEAP3.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • other_names：  
  • Six transmembrane epithelial antigen of prostate 3, dudulin-2
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • This STEAP3 antibody does not cross-react with other STEAP proteins.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction; mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.



 
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