Product Datasheet  
LGI1 Rabbit mAb  
Catalog Number: 78647  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • O95970
  • Form of Antibody:  
  • Storage:  
  • Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
  • Immunogen:  
  • Recombinant protein of human LGI1 .
  • reactivity:  
  • Human,Mouse,Rat
  • appl_detail:  
  • WB 1:500 - 1:2000
  • other_names:  
  • LGI1; ADLTE; ADPAEF; ADPEAF; EPITEMPIN; EPT; ETL1; IB1099; leucine rich glioma inactivated 1
  • Purification:  
  • Affinity purification
  • Specificity:  
  • Applications:  
  • WB
  • Background:  
  • This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.



 
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