Product Datasheet
LGI1 Rabbit mAb
Catalog Number: 78647
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Storage:
- Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
- Immunogen:
- Recombinant protein of human LGI1 .
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- LGI1; ADLTE; ADPAEF; ADPEAF; EPITEMPIN; EPT; ETL1; IB1099; leucine rich glioma inactivated 1
- Purification:
- Affinity purification
- Background:
- This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.
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