Product Datasheet  
[KO Validated] MyD88 Rabbit mAb  
Catalog Number: 78062  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Q99836
  • Form of Antibody：  
  • Storage：  
  • Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
  • Immunogen：  
  • A synthesized peptide derived from human MyD88
  • reactivity：  
  • Human
  • appl_detail：  
  • WB 1:500 - 1:2000
  • other_names：  
  • MYD88;MYD88D;myeloid differentiation primary response 88;MyD88
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]



 
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