Product Datasheet  
PD-1/CD279 Mouse mAb  
Catalog Number: 77822  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Q15116
  • Form of Antibody：  
  • Storage：  
  • Store at 4℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% thimerosal,0.05% BSA,pH7.3.
  • Immunogen：  
  • Recombinant protein of human PD-1/CD279.
  • reactivity：  
  • Human
  • appl_detail：  
  • IHC 1:50 - 1:200
  • other_names：  
  • PDCD1;CD279;PD-1;PD1;SLEB2;hPD-1;hPD-l;hSLE1
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • IHC
  • Background：  
  • This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.



 
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