Product Datasheet
[KO Validated] DNMT3A Rabbit mAb
Catalog Number: 77108
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Storage:
- Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
- Immunogen:
- A synthesized peptide derived from human DNMT3A.
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:500 - 1:2000
IP 1:50 - 1:200
- other_names:
- DNMT3A;DNMT3A2;M.HsaIIIA;TBRS;DNMT3A
- Purification:
- Affinity purification
- Background:
- CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. [provided by RefSeq, Mar 2016]
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