Product Datasheet
FKBP52 Antibody
Catalog Number: 49958
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q02790
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein within human FKBP52 aa 1-200.
- appl_detail:
- WB: 1:1,000-1:2,000
IHC: 1:50-1:200
ICC: 1:50-1:200
FC: 1:50-1:100
- other_names:
- 51 kDa FK506-binding protein antibody
52 kDa FK506 binding protein antibody
52 kDa FK506-binding protein antibody
52 kDa FKBP antibody
59 kDa immunophilin antibody
FK506 binding protein 4 antibody
FK506-binding
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC,IHC,FC
- Background:
- Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.
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