Product Datasheet  
EGR2 Antibody  
Catalog Number: 49927  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P11161
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:500-1:1,000



    FC: 1:50-1:100
  • other_names：  
  • AT591 antibody
    CMT1D antibody
    CMT4E antibody
    DKFZp686J1957 antibody
    E3 SUMO-protein ligase EGR2 antibody
    Early growth response 2 antibody
    Early growth response protein 2 antibody
    EGR-2 antibody
    e
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB,FC
  • Background：  
  • The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Binds to two specific DNA sites located in the promoter region of HOXA4. E3 SUMO-protein ligase helping SUMO1 conjugation to its coregulators NAB1 and NAB2, whose sumoylation down-regulates EGR2 own transcriptional activity. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.



 
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