Product Datasheet
Annexin IV Antibody
Catalog Number: 49926
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P09525
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein within human Annexin IV aa 1-200.
- appl_detail:
- WB: 1:500-1:2,000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
FC: 1:50-1:100
- other_names:
- 35 beta calcimedin antibody
35-beta calcimedin antibody
AIV antibody
Annexin 4 antibody
Annexin A4 antibody
Annexin IV (placental anticoagulant protein II) antibody
Annexin IV antibody
Annexin IV placent
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC,IF,IHC,FC
- Background:
- The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain which binds to phospholipids in a Ca++-dependent manner and a unique amino terminal region which may confer binding specificity. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. For example, the crystal structure of Annexin III has suggested a hydrophilic amino terminus with possible Ca++ channel activity. Similarly, Annexin V has ion channel properties. Annexin IV, also referred to as endonexin, functions to regulate Cl- flux by mediating calmodulin kinase II (CaMKII) activity and Annexin V has been shown to regulate PKC activity.
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