Product Datasheet  
Cellubrevin Antibody  
Catalog Number: 49902  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q15836
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Synthetic peptide conjugated to KLH within N-terminal human Cellubrevin.
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:500-1:2,000
    IHC: 1:50-1:200
    ICC: 1:50-1:200

    FC: 1:50-1:100
  • other_names:  
  • CEB antibody
    Cellubrevin antibody
    Synaptobrevin 3 antibody
    Synaptobrevin-3 antibody
    VAMP 3 antibody
    VAMP-3 antibody
    VAMP3 antibody
    VAMP3_HUMAN antibody
    Vesicle associated membrane protein 3 an
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB,ICC,IF,IHC,FC
  • Background:  
  • Vesicle-associated membrane proteins, known as VAMPs, also designated synaptobrevins, include VAMP-1, VAMP-2, VAMP-3 (cellubrevin), and synaptotagmin, a protein that may function as an inhibitor of exocytosis. VAMP proteins are vesicular factors that are important components of the machinery controlling docking and/or fusion of secretory vesicles with their target membrane. Synaptosomal-associated proteins, known as SNAPs, including alpha- and gamma-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. Pancreatic beta-cells express VAMP-2 and VAMP-3, and either one or both of these proteins selectively control Ca2+-mediated insulin secretion. In addition, VAMP-2 and VAMP-3 are expressed on GLUT4-containing vesicle membranes isolated from 3T3-Ll adipocytes and are important components of the insulin-dependent translocation of GLUT4 to the cell surface in adipocytes.



 
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