Product Datasheet
Cellubrevin Antibody
Catalog Number: 49902
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q15836
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Synthetic peptide conjugated to KLH within N-terminal human Cellubrevin.
- appl_detail:
- WB: 1:500-1:2,000
IHC: 1:50-1:200
ICC: 1:50-1:200
FC: 1:50-1:100
- other_names:
- CEB antibody
Cellubrevin antibody
Synaptobrevin 3 antibody
Synaptobrevin-3 antibody
VAMP 3 antibody
VAMP-3 antibody
VAMP3 antibody
VAMP3_HUMAN antibody
Vesicle associated membrane protein 3 an
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC,IF,IHC,FC
- Background:
- Vesicle-associated membrane proteins, known as VAMPs, also designated synaptobrevins, include VAMP-1, VAMP-2, VAMP-3 (cellubrevin), and synaptotagmin, a protein that may function as an inhibitor of exocytosis. VAMP proteins are vesicular factors that are important components of the machinery controlling docking and/or fusion of secretory vesicles with their target membrane. Synaptosomal-associated proteins, known as SNAPs, including alpha- and gamma-SNAP, are cytoplasmic proteins that bind to a membrane receptor complex composed of VAMP, SNAP 25 and syntaxin. Pancreatic beta-cells express VAMP-2 and VAMP-3, and either one or both of these proteins selectively control Ca2+-mediated insulin secretion. In addition, VAMP-2 and VAMP-3 are expressed on GLUT4-containing vesicle membranes isolated from 3T3-Ll adipocytes and are important components of the insulin-dependent translocation of GLUT4 to the cell surface in adipocytes.
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