Product Datasheet
SNF5 Antibody
Catalog Number: 49863
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q12824
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Synthetic peptide of C terminal Human SNF5.
- appl_detail:
- WB: 1:500-1:1,000
IHC: 1:50-1:100
FC: 1:50-1:100
- other_names:
- BAF47 antibody
BRG1-associated factor 47 antibody
hSNF5 antibody
INI1 antibody
Integrase interactor 1 protein antibody
Malignant rhabdoid tumor suppressor antibody
RDT antibody
RTPS1 antibody
Sfh
- Purification:
- ProA affinity purified
- Background:
- The SWI-SNF complex is involved in the activation of transcription via the remodeling of nucleosome structure in an ATP-dependent manner. Brm (also designated SNF2α) and Brg-1 (also designated SNF2β) are the ATPase subunits of the mammalian SWI-SNF complex. Brm, Brg-1, Ini1 (integrase interactor 1, also designated SNF5), BAF155 (also designated SRG3) and BAF170 are thought to comprise the functional core of the SWI-SNF complex. Addition of Ini1, BAF155 and BAF170 to Brg-1 appears to increase remodeling activity. Other complex subunits are thought to play regulatory roles. hSNF2L and hSNF2H both appear to be homologs of Drosophila ISWI, a Brm related ATPase that is present in chromatin remodeling complexes other than SWI/SNF, including the NURF (nucleosome remodeling factor).
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