Product Datasheet
GABA A Receptor alpha 5 Antibody
Catalog Number: 49791
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P31644
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
- other_names:
- GAA 5 antibody
GAA5 antibody
GABA(A) receptor subunit alpha-5 antibody
GABRA 5 antibody
Gabra5 antibody
Gamma aminobutyric acid GABA A receptor alpha 5 antibody
Gamma aminobutyric acid GABA A receptor alpha 5 p
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC,IF,IHC
- Background:
- GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Rα1-6, GABAA R β1-3, GABAA Rγ1-3, GABAA Rδ, GABAA Rε, GABAA R1 and GABAA R2. The GABAB family is composed of GABAB R1α and GABAB R1β. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.
© Signalway Biotechnology All Rights Reserved.