Product Datasheet  
DDX6 Antibody  
Catalog Number: 49789  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P26196
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:500-1:1,000
    IHC: 1:50-1:100


  • other_names：  
  • ATP dependent RNA helicase DDX6 antibody
    ATP dependent RNA helicase p54 antibody
    DDX6 antibody
    DEAD (Asp Glu Ala Asp) box polypeptide 6 antibody
    DEAD box 6 antibody
    DEAD box protein 6 antibody
    DEAD/H (Asp Glu Al
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB,IHC
  • Background：  
  • RCK, also known as DDX6 and P54, is a member of the DEAD-box RNA helicase family of proteins, all of which share common protein motifs. Found in most tissues, RCK is an unwindase that exhibits ATP-dependent RNA un-winding activity, as well as the ability to decay RNA in the 5'-3' direction. In non-malignant cells, RCK is associated with all processes of normal RNA metabolism including splicing, export and translation initiation. Mutations in the gene encoding RCK can cause the protein to be overexpressed, changing its function to that of an oncogene that positively regulates the expression of genes involved in cell growth and proliferation. It is believed that, through its unwindase activity, the main function of RCK is to downregulate mRNA expression and maintain normal transcriptional levels within the cell.



 
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