Product Datasheet  
ILF2 Antibody  
Catalog Number: 49780  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q12905
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:500
    IHC: 1:50-1:200

    IP: 1:10-1:20
    FC: 1:50-1:100
  • other_names:  
  • HGNC:6037 antibody
    ILF 2 antibody
    ilf2 antibody
    ILF2_HUMAN antibody
    Interleukin enhancer binding factor 2 antibody
    Interleukin enhancer binding factor 2, 45kDa antibody
    Interleukin enhancer-binding factor 2 anti
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB,IP,IHC,FC
  • Background:  
  • NF45 (ILF2, nuclear factor of activated T cells 45 kDa) is a transcription factor that interacts with NF90 (ILF3, DRBP76) to regulate gene expression. NF45 and NF90 are proteins that belong to the double-stranded RNA-binding protein family and both are substrates for the dsRNA-activated protein kinase, PKR. The NF45/NF90 heterodimer is mainly involved in regulating IL-2 expression by binding to the antigen receptor response element (ARRE) target sequence of the IL-2 enhancer. In neuronal cells, the NF45/NF90 heterodimer can repress human rhinovirus type 2 replication by binding to a 5' untranslated region of the viral RNA that encodes the internal ribosome entry site (IRES).



 
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