Product Datasheet
ILF2 Antibody
Catalog Number: 49780
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q12905
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:500
IHC: 1:50-1:200
IP: 1:10-1:20
FC: 1:50-1:100
- other_names:
- HGNC:6037 antibody
ILF 2 antibody
ilf2 antibody
ILF2_HUMAN antibody
Interleukin enhancer binding factor 2 antibody
Interleukin enhancer binding factor 2, 45kDa antibody
Interleukin enhancer-binding factor 2 anti
- Purification:
- ProA affinity purified
- Applications:
- WB,IP,IHC,FC
- Background:
- NF45 (ILF2, nuclear factor of activated T cells 45 kDa) is a transcription factor that interacts with NF90 (ILF3, DRBP76) to regulate gene expression. NF45 and NF90 are proteins that belong to the double-stranded RNA-binding protein family and both are substrates for the dsRNA-activated protein kinase, PKR. The NF45/NF90 heterodimer is mainly involved in regulating IL-2 expression by binding to the antigen receptor response element (ARRE) target sequence of the IL-2 enhancer. In neuronal cells, the NF45/NF90 heterodimer can repress human rhinovirus type 2 replication by binding to a 5' untranslated region of the viral RNA that encodes the internal ribosome entry site (IRES).
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