Product Datasheet  
ACTL6A Antibody  
Catalog Number: 49746  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:O96019
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein
  • reactivity:  
  • Hu, Ms
  • appl_detail:  
  • WB: 1:500-1:2,000
    IHC: 1:50-1:100
    ICC/IF: 1:50-1:100
    IP: 1:10-1:50
  • other_names:  
  • 53 kDa BRG1 associated factor A antibody
    53 kDa BRG1-associated factor A antibody
    ACL6A_HUMAN antibody
    Actin like 6A antibody
    Actin like protein 6A antibody
    Actin related protein 4 antibody
    Actin related protein
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB,ICC,IF,IHC,IP
  • Background:  
  • ACTL6A also named BAF53. The SWI/SNF complex regulates gene expression via ATP-dependent chromatin remodeling. Brm (SNF2-a), Brg-1 (SNF2-b), Ini1 (integrase interactor 1, SNF5), BAF53 (ARPnβ), BAF57, BAF155 (SRG3), and BAF170 make up the functional core. BAF53 homologues from yeast to humans contain a conserved N-terminal motif, which contains residues at serine 2 and tyrosine 6, which play important roles in BAF53 activity. The BAF53 protein shuttles between the nucleus and cytoplasm. BAF53 also forms a complex with TIP49 and TIP48, which mediates c-Myc oncogenic activity.



 
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