Product Datasheet
ACTL6A Antibody
Catalog Number: 49746
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O96019
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:500-1:2,000
IHC: 1:50-1:100
ICC/IF: 1:50-1:100
IP: 1:10-1:50
- other_names:
- 53 kDa BRG1 associated factor A antibody
53 kDa BRG1-associated factor A antibody
ACL6A_HUMAN antibody
Actin like 6A antibody
Actin like protein 6A antibody
Actin related protein 4 antibody
Actin related protein
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC,IF,IHC,IP
- Background:
- ACTL6A also named BAF53. The SWI/SNF complex regulates gene expression via ATP-dependent chromatin remodeling. Brm (SNF2-a), Brg-1 (SNF2-b), Ini1 (integrase interactor 1, SNF5), BAF53 (ARPnβ), BAF57, BAF155 (SRG3), and BAF170 make up the functional core. BAF53 homologues from yeast to humans contain a conserved N-terminal motif, which contains residues at serine 2 and tyrosine 6, which play important roles in BAF53 activity. The BAF53 protein shuttles between the nucleus and cytoplasm. BAF53 also forms a complex with TIP49 and TIP48, which mediates c-Myc oncogenic activity.
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