Product Datasheet  
PTBP1 Antibody  
Catalog Number: 49744  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P26599
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:500-1:2,000
    IHC: 1:50-1:200


  • other_names：  
  • 57 kDa RNA binding protein PPTB 1 antibody
    57 kDa RNA-binding protein PPTB-1 antibody
    Heterogeneous nuclear ribonucleoprotein I antibody
    Heterogeneous Nuclear Ribonucleoprotein Polypeptide I antibody
    hnRNP I antibody
    HN
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB,IHC
  • Background：  
  • Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10. In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation.



 
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