Product Datasheet  
EAAT3 Antibody  
Catalog Number: 49741  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P43005
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:500
    IHC: 1:50-1:200
    ICC/IF: 1:50-1:200

  • other_names:  
  • EAA3_HUMAN antibody
    EAAC 1 antibody
    EAAC1 antibody
    EAAT 3 antibody
    Excitatory amino acid carrier 1 antibody
    Excitatory amino acid carrier1 antibody
    Excitatory amino acid transporter 3 antibody
    Excitatory
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB,ICC,IF,IHC
  • Background:  
  • Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine. Functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion. Mediates Cl- flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na+ symport. Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. Negatively regulated by ARL6IP5.



 
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