Product Datasheet
EAAT3 Antibody
Catalog Number: 49741
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P43005
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:500
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
- other_names:
- EAA3_HUMAN antibody
EAAC 1 antibody
EAAC1 antibody
EAAT 3 antibody
Excitatory amino acid carrier 1 antibody
Excitatory amino acid carrier1 antibody
Excitatory amino acid transporter 3 antibody
Excitatory
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC,IF,IHC
- Background:
- Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate. Can also transport L-cysteine. Functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion. Mediates Cl- flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na+ symport. Plays an important role in L-glutamate and L-aspartate reabsorption in renal tubuli. Plays a redundant role in the rapid removal of released glutamate from the synaptic cleft, which is essential for terminating the postsynaptic action of glutamate. Negatively regulated by ARL6IP5.
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