Product Datasheet
TCTP Antibody
Catalog Number: 49734
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P13693
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:500-1:2,000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
FC: 1:50-1:100
- other_names:
- FLJ27337 antibody
Fortilin antibody
Histamine releasing factor antibody
Histamine-releasing factor antibody
HRF antibody
Immunoglobulin E-dependent antibody
p02 antibody
p23 antibody
TCTP antibody
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC/IF,IHC,FC,IP
- Background:
- Histamine-releasing factor (HRF) is a cytokine-like molecule that causes the release of histamine, IL-4 and IL-13 from basophils as well as the secretion of IL-8 and a calcium response in eosinophils. HRF belongs to the translationally controlled tumor protein (TCTP) family. It is expressed in several healthy and tumoral cells, including erythrocytes, hepatocytes, macrophages, platelets, keratinocytes, erythroleukemia cells, gliomas, melanomas, hepatoblastomas and lymphomas, and it is localized in the cytoplasm. HRF plays a pivotal role in allergic diseases, and due to its wide distribution in brain, is thought to be involved in neurodegenerative disorders, such as Alzheimer's disease and Down syndrome.
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