Product Datasheet
GPX4 Antibody
Catalog Number: 49731
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P36969
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- reactivity:
- Hu, Ms, Rt, Zebrafish
- appl_detail:
- WB: 1:500-1:2,000
IHC: 1:50-1:200
- other_names:
- Glutathione peroxidase 4 antibody
GPX 4 antibody
GPX-4 antibody
GPX4 antibody
GPX4_HUMAN antibody
GSHPx-4 antibody
MCSP antibody
mitochondrial antibody
PHGPx antibody
Phospholipid hydroperoxidase antibody
Phospholip
- Purification:
- ProA affinity purified
- Background:
- Glutathione peroxidase (GPx) enzymes are generally selenium-containing tetrameric glycoproteins that help prevent lipid peroxidation of cell membranes. GPx enzymes reduce lipid hydroperoxides to alcohols, and reduce free hydrogen peroxide to water. GPx members are among the few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by the nonsense (stop) codon TGA. There are eight GPx homologs (GPx-1-8). GPx-1, Gpx-2 and Gpx-3 exist as homotetramers. Gpx-4 has a high tendancy to form high molecular weight oligomers.
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