Product Datasheet
alpha Internexin Antibody
Catalog Number: 49709
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q16352
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:1,000-5,000
IHC: 1:50-1:200
ICC: 1:50-1:200
FC: 1:50-1:100
- other_names:
- 66 kDa neurofilament protein antibody
AINX_HUMAN antibody
Alpha Inx antibody
Alpha-internexin antibody
Alpha-Inx antibody
INA antibody
Internexin neuronal intermediate filament protein alpha antibody
MG
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC/IF,IHC,FC,IP
- Background:
- Alpha-internexin is a brain specific type IV intermediate filament protein. This axonal protein is found in most, if not all, neurons of the CNS. The head domain of alpha-internexin is essential for self-assembly into a filament network. Expression levels of alpha-internexin have been shown to be maximal during late embryogenesis and to decline into adulthood, suggesting that this protein plays a role in regulatory processes during the development of the brain. The alpha-internexin promoter has been shown to be activated by Brn-3a or Brn-3c transcription factor binding, while Brn-3b binding to the promoter results in alpha-internexin repression.
© Signalway Biotechnology All Rights Reserved.