Product Datasheet
Plexin A1 Antibody
Catalog Number: 49704
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9UIW2
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
ICC: 1:50-1:200
FC: 1:50-1:100
- other_names:
- NOV antibody
NOV/plexin A1 protein antibody
NOVP antibody
Plexin-A1 antibody
Plexin1 antibody
PlexinA1 antibody
PLXA1_HUMAN antibody
PLXN1 antibody
Plxna1 antibody
PLXNA1 protein antibod
- Purification:
- ProA affinity purified
- Background:
- Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
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