Product Datasheet
USP22 Antibody
Catalog Number: 49701
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9UPT9
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:1,000-5,000
ICC: 1:50-1:200
IP: 1:10-1:50
FC: 1:50-1:100
- other_names:
- Deubiquitinating enzyme 22 antibody
KIAA1063 antibody
Ubiquitin carboxyl terminal hydrolase 22 antibody
Ubiquitin carboxyl-terminal hydrolase 22 antibody
Ubiquitin specific peptidase 22 antibody
Ubiquitin specific pe
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC/IF,FC,IP
- Background:
- The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. Through the use of a wide range of enzymes that can add or remove ubiquitin, the Ub pathway controls many intracellular processes such as signal transduction, transcriptional activation and cell cycle progression. USP22 (ubiquitin specific peptidase 22), also known as USP3L, is a 525 amino acid protein that contains one UBP-type zinc finger and functions to catalyze the conversion of a ubiquitin C-terminal thioester to free ubiquitin and thiol, a reaction that may influence several cellular processes. Via its catalytic activity, USP22 is thought to play an important role in cell cycle progression and may also serve as a cancer stem cell marker. The gene encoding USP22 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes.
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