Product Datasheet  
PDX1 Antibody  
Catalog Number: 49689  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P52945
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu
  • appl_detail：  

  • IHC: 1:50-1:200
    ICC/IF: 1:50-1:200

  • other_names：  
  • Glucose sensitive factor antibody
    Glucose-sensitive factor antibody
    GSF antibody
    IDX 1 antibody
    IDX-1 antibody
    IDX1 antibody
    Insulin promoter factor 1 antibody
    Insulin promoter factor 1 homeod
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, IHC, ICC/IF
  • Background：  
  • Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.



 
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