Product Datasheet  
Histone H2A.X Antibody  
Catalog Number: 49687  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P16104
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1500-12000
    IHC: 1:100-1:500

    IP: 1:10-1:50
  • other_names：  
  • AW228881 antibody
    H2A histone family member X antibody
    H2A.FX antibody
    H2A.X antibody
    H2a/x antibody
    H2AFX antibody
    H2AX antibody
    H2AX histone antibody
    H2AX_HUMAN antibody
    Hi
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, IF/ICC, IHC, IP
  • Background：  
  • Histone H2A.X is a member of the Histone H2A family, which is involved in nucleosomal organization of chromatin. The H2AFX gene is located in close proximity to the Porphobilinogen deaminase (PBG-D) gene in both mouse and human, and maps to chromosome 9 and 11q23, respectively. H2A.X meets from the other members of the H2A family by the presence of a highly conserved C-terminal motif. It is wide phosphorylated in response to ionizing radiation and plays an important role in the recognition and repair of DNA fragments are involved in the heavy chain constant region of cells involved in class switch recombination (CSR), a region-specific DNA reaction that replaces one immunoglobulin heavy chain constant region gene with another. The phosphorylated γ-H2A.X is also thought to firing new grades factors, including Rad50, Rad51 and BRCA1.



 
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