Product Datasheet
Aldolase Antibody
Catalog Number: 49682
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P04075
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- reactivity:
- Hu, Ms, Rt, Zebrafish
- appl_detail:
- WB: 1:500-1:2,000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
- other_names:
- ALDA antibody
Aldo1 antibody
ALDOA antibody
ALDOA_HUMAN antibody
Aldolase 1 antibody
Aldolase A antibody
Aldolase A fructose bisphosphatase antibody
Aldolase A fructose bisphosphate antibody
Aldolase, fructose-bisphosphate
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC,IF,IHC
- Background:
- Fructose 1,6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1,6-bisphosphate. Fructose 1,6-bisphosphate aldolase exists as three forms: the muscle-specific Aldolase A; the liver-specific Aldolase B; and the brain-specific Aldolase C. Aldolase A, B and C arose from a common ancestral gene from which Aldo-lase B first diverged. Aldolase A is one of the most highly-conserved enzymes known, with only about 2% of the residues changing per 100 million years. Aldolase B is regulated by the hormones insulin and glucagon, and has been implicated in hereditary fructose intolerance disease. Aldolase C is a polypeptide that is exclusively expressed in Purkinje cells. Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase C-negative Purkinje cells.
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