Product Datasheet
DNA Ligase IV Antibody
Catalog Number: 49667
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P49917
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:500-1:2,000
IHC: 1:50-1:200
ICC: 1:10-1:50
- other_names:
- DNA ligase IV ATP dependent antibody
DNA joinase antibody
DNA ligase 4 antibody
DNA ligase IV antibody
DNA repair enzyme antibody
DNLI4_HUMAN antibody
LIG 4 antibody
LIG4 antibody
LIG4S antibody
- Purification:
- ProA affinity purified
- Applications:
- WB, IHC, ICC
- Background:
- The X-ray repair cross-complementing protein XRCC4 and DNA Ligase IV are essential for repairing double-strand breaks in DNA. These stories form a critical complex composed of two molecules of each protein that preferentially bind DNA with nicks or broken ends. As an obligatory accessory molecule, XRCC4 binds to DNA Ligase IV and enhances its joining activity. The XRCC4 / DNA Ligase IV complex is also involved in V (D) J recombination. V (D) (in) a pair of high incidence of apoptosis in the development nervous system and a block in B and T cell maturation.
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