Product Datasheet
PGC1 beta Antibody
Catalog Number: 49655
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q86YN6
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:500-1:2,000
IP: 1:10-1:50
FC: 1:50-1:200
- other_names:
- PERC antibody
peroxisome proliferative activated receptor, gamma, coactivator 1, antibody
peroxisome proliferator-activated receptor gamma coactivator 1 beta antibody
Peroxisome proliferator-activated receptor gamma coactivator
- Purification:
- ProA affinity purified
- Background:
- Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcritional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.
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