Product Datasheet
GABARAP Antibody
Catalog Number: 49642
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O95166
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:500
IHC: 1:50-1:200
FC: 1:50-1:100
- other_names:
- ATG8A antibody
FLC 3B antibody
FLC3B antibody
FLJ25768 antibody
GABA type A receptor associated protein antibody
GABA(A) receptor associated protein antibody
GABA(A) receptor-associated protein antibody
GAB
- Purification:
- ProA affinity purified
- Applications:
- WB, IHC, FC
- Background:
- In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl-conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. In addition to GABA receptors, several proteins have been identified as regulators of GABA function, including GAD65, GAD67, GABA transporters and GABARAP (GABAA receptor-associated protein). GABARAP associates with GABAA Rg2 to link GABAA receptors to the cytoskeleton. The GABARAP protein sequence is similar to light chain-3 of microtubule-associated proteins (MAPs) suggesting that it may be a type of MAP or a component of a MAP complex.
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