Product Datasheet
PKC mu Antibody
Catalog Number: 49629
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q15139
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:500-1:2,000
- other_names:
- KPCD1_HUMAN antibody
nPKC D1 antibody
nPKC mu antibody
nPKC-D1 antibody
nPKC-mu antibody
nPKCD1 antibody
nPKCmu antibody
PKC antibody
PKC MU antibody
PKCM antibody
PKCmu antibody
PKD 1 anti
- Purification:
- ProA affinity purified
- Background:
- Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. In epithelial cells, is required for transducing flagellin-stimulated inflammatory responses by binding and phosphorylating TLR5, which contributes to MAPK14/p38 activation and production of inflammatory cytokines. May play a role in inflammatory response by mediating activation of NF-kappa-B. May be involved in pain transmission by directly modulating TRPV1 receptor. Plays a role in activated KRAS-mediated stabilization of ZNF304 in colorectal cancer (CRC) cells. Regulates nuclear translocation of transcription factor TFEB in macrophages upon live S.enterica infection.
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