Product Datasheet
PKC beta 1 Antibody
Catalog Number: 49623
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P05771
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:500
IHC: 1:50-1:200
FC: 1:50-1:100
- other_names:
- BTN6 antibody
BTNL11 antibody
MGC26137 antibody
MOG alpha 5 antibody
MOG alpha 6 antibody
MOG AluA antibody
MOG AluB antibody
MOG antibody
MOG Ig AluB antibody
MOG_HUMAN antibody
MOGIG2
- Purification:
- ProA affinity purified
- Applications:
- WB, IHC, FC
- Background:
- Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (α, βI, βII and γ) and novel (n) PKC isoformsandν. Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC δ and ε are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.
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