Product Datasheet  
NDRG1 Antibody  
Catalog Number: 49614  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q92597
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:500-1:2,000
    IHC: 1:50-1:200
    ICC: 1:50-1:200
    IP: 1:50
  • other_names:  
  • 42 kDa antibody
    Anti GC4 antibody
    cap43 antibody
    cmt4d antibody
    Differentiation related gene1 protein antibody
    Differentiation-related gene 1 protein antibody
    Drg 1 antibody
    DRG-1 antibody
    drg1 antibody
    gc4 ant
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC/IF, IHC, IP
  • Background:  
  • The N-myc downstream regulated gene (NDRG) family is comprised of four members, NDRG1 (also designated Drg1, RTP, rit42, Cap43 and Ndr1), NDRG2, NDRG3 and NDRG4, which share 57-65% homology. The NDRG1 gene, which maps to human chromosome 8q24.22, is evolutionarily conserved and is similarly regulated in humans, mice and rats . Like NDRG2 and NDRG3, NDRG1 is ubiquitously expressed, but it is expressed most prominently in placental membranes and prostate, kidney, small intestine and ovary tissue. NDRG1 gene expression is induced by several compounds, including nickel, and produces a protein involved in stress responses, hormone responses, cell growth and differentiation. The gene encoding NDRG3 maps to human chromosome 20q11.23 and is predominantly expressed in testis, prostate and ovary, which suggests it may play a role in spermatogenesis.



 
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