Product Datasheet
OGG1 Antibody
Catalog Number: 49583
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O15527
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:500
IHC: 1:50-1:200
- other_names:
- 8 hydroxyguanine DNA glycosylase antibody
8 oxoguanine DNA glycosylase 1 antibody
8 oxoguanine DNA glycosylase antibody
AP lyase antibody
DNA (apurinic or apyrimidinic site) lyase antibody
DNA apurinic or apyrimidinic si
- Purification:
- ProA affinity purified
- Background:
- DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. The OGG1 gene encodes 8 isoforms (OGG1A-C, OGG2A-E) which result from alternative splicing of a single messenger RNA. The OGG1A splice variant is the most prevalent form and localizes to the nucleus, whereas the OGG2A splice variant is targeted to the mitochondria.
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