Product Datasheet  
OGG1 Antibody  
Catalog Number: 49583  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:O15527
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein
  • reactivity:  
  • Hu
  • appl_detail:  
  • WB: 1:500
    IHC: 1:50-1:200


  • other_names:  
  • 8 hydroxyguanine DNA glycosylase antibody
    8 oxoguanine DNA glycosylase 1 antibody
    8 oxoguanine DNA glycosylase antibody
    AP lyase antibody
    DNA (apurinic or apyrimidinic site) lyase antibody
    DNA apurinic or apyrimidinic si
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, IHC
  • Background:  
  • DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. The OGG1 gene encodes 8 isoforms (OGG1A-C, OGG2A-E) which result from alternative splicing of a single messenger RNA. The OGG1A splice variant is the most prevalent form and localizes to the nucleus, whereas the OGG2A splice variant is targeted to the mitochondria.



 
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