Product Datasheet
Phosphotyrosine Antibody
Catalog Number: 49532
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Synthetic peptide conjugated to Keyhole Limpet Haemocyanin (KLH)
- appl_detail:
- WB: 1:50-1:200
ICC: 1:50
FC: 1:10-1:50
- Purification:
- ProA affinity purified
- Applications:
- WB, ICC/IF, IP, FC
- Background:
- Tyrosine phosphorylation plays a key role in cellular signaling. Research studies have shown that in cancer, unregulated tyrosine kinase activity can drive malignancy and tumor formation by generating inappropriate proliferation and survival signals. Antibodies specific for phospho-tyrosine have been invaluable reagents in these studies. The phospho-tyrosine monoclonal antibodies developed by Cell Signaling Technology are exceptionally sensitive tools for studying tyrosine phosphorylation and monitoring tyrosine kinase activity in high throughput drug discovery.
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