Product Datasheet
Rhodopsin Antibody
Catalog Number: 49524
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P08100
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:500-1:1,000
IHC: 1:50-1:200
- other_names:
- CSNBAD1 antibody
MGC138309 antibody
MGC138311 antibody
OPN 2 antibody
OPN2 antibody
opsd antibody
OPSD_HUMAN antibody
opsin 2 antibody
Opsin 2 rod pigment antibody
Opsin-2 antibody
Opsi
- Purification:
- ProA affinity purified
- Background:
- In aerobic respiration reactions, succinate dehydrogenase (SDH) catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol. Four subunits comprise the SDH protein complex: a flavochrome subunit (SDHA), an iron-sulfur protein (SDHB), and two membrane-bound subunits (SDHC and SDHD) anchored to the inner mitochondrial membrane. Mutations to these subunits cause mitochondrial dysfunction, corresponding to several distinct disorders. Mutations in the membrane bound components may cause hereditary paraganglioma, while SDHA mutations are associated with juvenile encephalopathy as well as Leigh Syndrome, a severe neurological disorder. Inactivating mutations in SDHB correlate with inherited, but not necessarily sporadic, cases of pheochromocytoma.
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