Product Datasheet
TIMP2 Antibody
Catalog Number: 49494
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P16035
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:500-1:2,000
FC: 1:10-1:50
- other_names:
- CSC 21K antibody
CSC-21K antibody
CSC21K antibody
Metalloproteinase inhibitor 2 antibody
Metalloproteinase inhibitor 2 precursor antibody
TIMP 2 antibody
TIMP metallopeptidase inhibitor 2 antibody
TIMP-2 an
- Purification:
- ProA affinity purified
- Background:
- TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases 1, 2, 3 and 4) complex with metalloproteinases such as collagenases, gelatin-ases and stromelysins, resulting in irreversible inactivation of the metallopro-teinase. TIMP-1 has been found to be identical to EPA (erythroid-potentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus and remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart, with low levels expressed in liver, brain, lung, thymus and spleen.
© Signalway Biotechnology All Rights Reserved.