Product Datasheet  
TIMP2 Antibody  
Catalog Number: 49494  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P16035
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • recombinant protein
  • reactivity:  
  • Hu
  • appl_detail:  
  • WB: 1:500-1:2,000



    FC: 1:10-1:50
  • other_names:  
  • CSC 21K antibody
    CSC-21K antibody
    CSC21K antibody
    Metalloproteinase inhibitor 2 antibody
    Metalloproteinase inhibitor 2 precursor antibody
    TIMP 2 antibody
    TIMP metallopeptidase inhibitor 2 antibody
    TIMP-2 an
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, FC
  • Background:  
  • TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases 1, 2, 3 and 4) complex with metalloproteinases such as collagenases, gelatin-ases and stromelysins, resulting in irreversible inactivation of the metallopro-teinase. TIMP-1 has been found to be identical to EPA (erythroid-potentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus and remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart, with low levels expressed in liver, brain, lung, thymus and spleen.



 
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