Product Datasheet  
Clathrin heavy chain Antibody  
Catalog Number: 49560  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P53675
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • recombinant protein
  • reactivity:  
  • Hu, Ms,Rt
  • appl_detail:  
  • WB: 1:500-1:2,000
    IHC: 1:50-1:200


  • other_names:  
  • CHC17 antibody
    Clathrin heavy chain antibody
    Clathrin heavy chain 1 antibody
    Clathrin heavy chain 2 antibody
    Clathrin heavy chain like 1 antibody
    Clathrin heavy chain on chromosome 17 antibody
    Clathrin heavy polypeptide
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, IHC
  • Background:  
  • Clathrin is a major cytosolic coat protein in pits and vesicles originating from the plasma membrane and the trans-Golgi network. In receptor-mediated endocytosis, receptor proteins are englufed by clathrin-coated vesicles. Clathrin is composed of three heavy chains and three light chains which associate non-covalently to form a triskelion structure. Clathrin heavy chain (HC) is composed of a terminal globular domain, a distal segment and a proximal segment containing a light chain binding site. The proximal segment of the Clathrin HC protein is essential for interactions between clathrin heavy chains and light chains which result in the formation of the triskelion structure.



 
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