Product Datasheet
TGN46 Antibody
Catalog Number: 49370
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O43493
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1,000-1:2,000
IHC: 1:50-1:200
IP: 1:50-1:100
- other_names:
- TGN 46 antibody TGN 51 antibody TGN38 antibody TGN38 homolog antibody TGN46 antibody TGN48 antibody TGN51 antibody TGOLN2 antibody TGON2_HUMAN antibody Trans Golgi network integral membrane protein 2 antibody
- Purification:
- ProA affinity purified
- Applications:
- WB, IHC, IP
- Background:
- TGN38 (trans-Golgi network protein 2) is a type I integral membrane protein that constitutively cycles between the TGN and plasma membrane where it partitions nascent proteins into carrier vesicles for transport to appropriate destinations in the cell. The cytosolic domain of TGN38 interacts with AP2 Clathrin adaptor complexes via the tyrosine-containing motif (SDYQRL) to direct internalization from the plasma membrane. N- and O-linked oligosaccharide chains attach to the core TGN38 protein to produce a protein present in brain, lung and kidney.
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