Product Datasheet  
VE Cadherin Antibody  
Catalog Number: 49308  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P55284
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • recombinant protein
  • reactivity：  
  • Ms
  • appl_detail：  
  • WB: 1:1,000-5,000



  • other_names：  
  • 7B 4 antibody
    7B4 antibody
    7B4 antigen antibody
    CADH5_HUMAN antibody
    Cadherin 5 antibody
    Cadherin 5 type 2 antibody
    Cadherin 5, type 2 (vascular endothelium) antibody
    Cadherin 5, type 2, VE cadherin (vascular epithelium)
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB,IP
  • Background：  
  • The cadherins are a family of Ca2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy-terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. VE-cadherin (for vascular endothelial cadherin, also designated cadherin-5) is localized at intercellular junctions of endothelial cells, where it is thought to play a role in the cohesion and organization of intercellular junctions.



 
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