Product Datasheet
IGF2 Antibody
Catalog Number: 49302
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P01344
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1,000
IHC: 1:50-1:200
ICC: 1:100-1:500
- other_names:
- C11orf43 antibody IGF 2 antibody IGF II antibody IGF-II antibody IGF2 antibody IGF2_HUMAN antibody IGFII antibody INSIGF antibody insulin like growth factor 2 (somatomedin A) antibody Insulin like Growth Factor
- Purification:
- ProA affinity purified
- Applications:
- WB, ICC/IF, IHC
- Background:
- IGF-II (Insulin-like growth factor II; also multiplication-stimulating polypeptide/MSP and somatomedin-A) is a secreted 8 kDa polypeptide that belongs to the insulin family of peptide growth factors. It is part of a complex system of growth and metabolic-regulating proteins that is particularly important during development. It has been associated with nervous system proliferation and differentiation, myelination, adrenal cortical proliferation, and skeletal growth and differentiation. In human, IGF-II is primarily synthesized by the liver, and circulates at high levels in both fetus and adult. In rodent, however, IGF-II levels drop after the perinatal period, an effect attributed to the lack of a key gene promoter. This may indicate that postnatally, IGF-II has either a limited, or local effect only in rodent.
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