Product Datasheet
PKC delta Antibody
Catalog Number: 49299
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q05655
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1,000-1:2,000
IHC: 1:50-1:200
ICC: 1:50-1:200
- other_names:
- CVID9 antibody
D14Ertd420e antibody
Kinase PKC delta antibody
KPCD antibody
KPCD_HUMAN antibody
MAY 1 antibody
MAY1 antibody
MGC49908 antibody
nPKC delta antibody
nPKC-delta antibody
PC
- Purification:
- ProA affinity purified
- Applications:
- WB, ICC/IF, IHC
- Background:
- Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (α, βI, βII and γ) and novel (n) PKC isoforms (δ, ε, ζ, η, θ, λ/ι, μ and ν). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC δ and ε are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.
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