Product Datasheet
ZNRF2 Antibody
Catalog Number: 49291
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8NHG8
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1,000-1:2,000
IHC: 1:50-1:200
- other_names:
- E3 ubiquitin-protein ligase ZNRF2 antibody Protein Ells2 antibody RING finger protein 202 antibody RNF202 antibody Zinc/RING finger protein 2 antibody Znrf2 antibody ZNRF2_HUMAN antibody
- Purification:
- ProA affinity purified
- Background:
- NF-E2 related factor 2 (Nrf2) is a member of the cap n collar family of basic leucine zipper transcription factors. By binding antioxidant response elements (AREs), Nrf2 activates the transcription of genes encoding antioxidant and phase II drug-metabolizing enzymes needed to protect cells against oxidative damage. Transcriptional targets regulated by Nrf2 include genes encoding glutathione S-transferases, superoxide dismutase-1, and heme oxygenase-1.
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