Product Datasheet  
SDF1 Antibody  
Catalog Number: 49290  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P48061
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • recombinant protein
  • reactivity:  
  • Hu
  • appl_detail:  
  • WB: 1:1,000-1:2,000

    ICC: 1:50-1:200

  • other_names:  
  • 12-O-tetradecanoylphorbol 13-acetate repressed protein 1 antibody
    AI174028 antibody
    C-X-C motif chemokine 12 antibody
    Chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1) antibody
    Chemokine (C-X-C motif) ligand 12 antibody
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC/IF
  • Background:  
  • The stromal cell derived factor 1 (SDF1, CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1 isoforms (SDF1α and SDF1β) that have different properties and biological activities. Additional isoforms of SDF1 have been reported.



 
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