Product Datasheet  
Estrogen Receptor beta Antibody  
Catalog Number: 49281  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q92731
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • recombinant protein
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:1,000-1:2,000



  • other_names：  
  • ER BETA antibody
    ER-beta antibody
    Erb antibody
    ESR B antibody
    ESR BETA antibody
    ESR2 antibody
    ESR2_HUMAN antibody
    ESRB antibody
    ESTRB antibody
    estrogen nuclear receptor beta variant a antibody
    estrogen nuc
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors. Estrogen receptors, including ERα and ERβ, contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues. They are located in the nucleus, though some estrogen receptors associate with the cell surface membrane and can be rapidly activated by exposure of cells to estrogen. ERα and ERβ have been shown to be differentially activated by various ligands. Receptor-ligand interactions trigger a cascade of events, including dissociation from heat shock proteins, receptor dimerization, phosphorylation and the association of the hormone activated receptor with specific regulatory elements in target genes. Evidence suggests that ERα and ERβ may be regulated by distinct mechanisms even though they share many functional characteristics.



 
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